What is the mechanism of action of ondansetron?
- Dopamine D₂ receptor antagonism in the chemoreceptor trigger zone
- Selective 5-HT₃ receptor antagonism in the gastrointestinal tract and central nervous system
- Histamine H₁ receptor antagonism in the vestibular system
- Neurokinin-1 (NK₁) receptor antagonism in the area postrema