2024 - Multiple Choice Questions

Which drug has the longest elimination half-life?
  1. Digoxin
  2. Glycopyrrolate
  3. Milrinone
  4. Vasopressin
What is the PaO2 in the coronary sinus?
  1. 20mmHg
  2. 40mmHg
  3. 60mmHg
  4. 80mmHg
Propranolol is a competitive antagonist at adrenoreceptors. What effect would Propranolol have on a dose-response curve for Adrenaline?
  1. left shift
  2. right shift
  3. downward shift
  4. upward shift
Which of the following has the lowest pressure?
  1. Pleural Pressure
  2. Mean Systemic Filling Pressure
  3. Right Atrial Pressure
  4. Right Ventricular Pressure
The Dorsal Respiratory group of chemoreceptors are located near the nuclei for the:
  1. Facial and Glossopharyngeal nerves
  2. Vagus and Glossopharyngeal nerves
  3. Vagus and Accessory nerves
  4. Vagus and vestibular nerves
At the apex of the lung, compared with the base:
  1. Pleural pressure increases
  2. PO2 increases
  3. Compliance increases
  4. Airway resistance increases
Digoxin’s direct mechanical mechanism of action is via:
  1. Inhibition of Na/K/ATPase to increase intracellular Ca++
  2. Inhibition of Na/K/ATPase to increase automaticity
  3. Inhibition of Na/K/ATPase to depolarise smooth muscle
  4. Sensitization of carotid sinus baroreceptors
The largest amplitude on an oscillometer correlates closely to:
  1. Pulse point
  2. Systolic Blood Pressure
  3. Diastolic Blood Pressure
  4. Mean Arterial Pressure
One gram of adult haemoglobin can carry how many ml of O2:
  1. 1.39
  2. 1.37
  3. 1.36
  4. 1.34
During periods of starvation
  1. glycogen stores are depleted in 48hrs
  2. amino acids are converted to glucose
  3. tissue breakdown initially provides 900 calories per day
  4. urinary nitrogen loss progressively increases
The water content in a gas sample measured from the expiratory limb of a ventilator for a patient in ICU is 22mg/L at 37 degress Celcius. Which statement is correct?
  1. The absolute humidity is 22mg/L
  2. The absolute humidity cannot be calculated
  3. The relative humidity is 22%
  4. The relative humidity cannot be calculated
Gabapentin exerts its pharmacological effect on
  1. Calcium channels
  2. Sodium channels
  3. GABAA receptors
  4. Alpha2 adrenergic receptors
Ischaemic cardiac pain is transmitted by:
  1. A-delta nerve fibres
  2. Sympathetic nerve fibres
  3. Nerve fibres that synapse in the dorsal root ganglion
  4. Special visceral afferent fibres
Hydralazine is best described as a:
  1. K+ antagonist
  2. Na+ antagonist
  3. Direct Vasodilator
  4. Venodilator and vasodilator
Which cephalosporin has the highest proportion of biliary excretion:
  1. Cephazolin
  2. Ceftriaxone
  3. Ceftazidime
  4. Cefotaxime
What is the maximum capacity for water absorption in the large bowel each day?
  1. 2-3L
  2. 5-6L
  3. 8-9L
  4. 10-11L
COX-2 inhibitors may mediate bleeding via inhibition of:
  1. Prostaglandins
  2. Platelet production
  3. GPIIB-IIIA receptors
  4. Thromboxane A2
In addition to being a non-selective beta-blocker, Propranolol is also:
  1. An alpha-1 antagonist
  2. A sodium channel blocker
  3. A Beta-2 agonist
  4. A potassium channel blocker
Which process is required to convert Noradrenaline to Adrenaline?
  1. Hydroxylation
  2. Reduction
  3. Decarboxylation
  4. Methylation
Which immunoglobulin is able to cross the placenta?
  1. IgA
  2. IgE
  3. IgG
  4. IgM