Skip to content
Home
Syllabus
New Syllabus Topics Fourth Edition (2023)
A – Pharmaceutics
B – Pharmacokinetics
C – Pharmacodynamics
D – Variability in Drug Response
E – Cellular Physiology
F – Respiratory System
G – Cardiovascular System
H – Renal System
I – Body Fluids and Electrolytes
J – Acid Base
K – Nervous System – Including Pain
L – Musculoskeletal System
M – Autonomic Nervous System
N – Liver
O – Gastrointestinal System
P – Nutrition & Metabolism
Q – Haematological System
R – Thermoregulation
S – Immunology & Host Defence
T – Microbiology
U – Endocrine System
V – Obstetrics
W – Principles of Measurement and Equipment
X – Procedural Anatomy
Year
Pharmacopeia
MCQs
2023
2022
2021
2020
2019
MPS
Test Yo’Self
Hacks
About
Menu
Home
Syllabus
New Syllabus Topics Fourth Edition (2023)
A – Pharmaceutics
B – Pharmacokinetics
C – Pharmacodynamics
D – Variability in Drug Response
E – Cellular Physiology
F – Respiratory System
G – Cardiovascular System
H – Renal System
I – Body Fluids and Electrolytes
J – Acid Base
K – Nervous System – Including Pain
L – Musculoskeletal System
M – Autonomic Nervous System
N – Liver
O – Gastrointestinal System
P – Nutrition & Metabolism
Q – Haematological System
R – Thermoregulation
S – Immunology & Host Defence
T – Microbiology
U – Endocrine System
V – Obstetrics
W – Principles of Measurement and Equipment
X – Procedural Anatomy
Year
Pharmacopeia
MCQs
2023
2022
2021
2020
2019
MPS
Test Yo’Self
Hacks
About
Search
Search
Syllabus
D:
Variability in Drug Response
Di: Classify and describe adverse drug reactions
Di / 17B16: Classify and describe adverse drug reactions with examples of each
Dii: Classify and describe mechanisms of drug interaction
Dii / 21B15 / 17A03 / 15A09: Classify and describe mechanisms of drug interactions with examples
Diii :Describe variability in drug responses due to physiological changes with reference to neonates/infants, the elderly, pregnancy, and obesity
Diii: Describe the effects of obesity on drug pharmacology and give examples of drugs to illustrate
Diii: Outline the pharmacokinetic consequences of old age with examples
Div: Describe variability in drug responses due to critical illness
Div: How does liver failure affect pharmacology of drugs
Div: Loading dose, maintenance dose & critically ill
Div: Outline alterations to drug response due to critical illness
Dv: Define tachyphylaxis, tolerance, addiction, dependence and idiosyncrasy
Dv: Define Tachyphylaxis, Tolerance, Addiction, Dependence & Idiosyncrasy
Dvi: Describe mechanisms of tolerance
Dvi / 14B15: Define the terms tolerance and tachyphylaxis (20 marks). Describe the different mechanisms by which tolerance can develop and give examples of each (80 marks)
Dvii: Outline genetic variability, mechanisms, and significance of pharmacogenetic disorders. (e.g., malignant hyperthermia, porphyria, atypical cholinesterase, and disturbance of cytochrome function)
Dvii: Outline genetic variability
Dvii: Discuss factors contributing to the inter-individual variability in response to opioid analgesics
Dvii: Explain the mechanisms and significance of pharmacogenetic disorders
Dviii: Describe isomerism and outline the clinical importance of isomerism, providing examples
Dviii: Describe & give examples of the clinical importance of isomerism