Jenny's Jam Jar

2019 - Multiple Choice Questions

2019

1.
Which haemodynamic changes are observed in Phase II of the Valsalva Manoeuvre?
  1. Hypotension and increased venous return
  2. Hypotension and tachycardia
  3. Hypertension and bradycardia
  4. Hypertension and reduced venous return
2.
Mechanism of Sodium Thiosulphate metabolism:
  1. Oxidation (to pentobarbital)
  2. Renal elimination unchanged
  3. Reduction
  4. Hydrolysis
3.
Which additive of propofol retards bacterial growth?
  1. Soyabean Oil (intralipid)
  2. Sodium Hydroxide (brings pH > 7)
  3. Edetate Disodium
  4. Glycerol (isotonicity)
4.
At which temperature are platelets best stored at?
  1. 0-4 C
  2. 2-6 C
  3. 20-24C
  4. < -25 C
5.
Which pathway describes the excretion and metabolism of rocuronium?
  1. Hoffman elimination
  2. Plasma cholinesterase
  3. Non specific ester hydrolysis
  4. Liver metabolism and excretion
6.
Which of these describes the pressures acting on the lung
  1. Mouth Pressure – Alveolar Pressure
  2. Alveolar Pressure – Pleural Pressure
  3. Alveolar Pressure – Atmospheric Pressure
  4. Alveolar Pressure – Abdominal Abdominal
7.
Eccrine sweat glands:
  1. Are innervated by parasympathetic fibers releasing acetylcholine from their post synaptic fibers
  2. Are innervated by parasympathetic fibers releasing noradrenaline from their post synaptic fibers
  3. Are innervated by sympathetic fibers releasing acetylcholine from their post synaptic fibers
  4. Are innervated by sympathetic fibers releasing noradrenaline from their post synaptic fibers
8.
According to the oxygen cascade, which of the following has the lowest oxygen tension?
  1. End expiratory gas
  2. Mitochondria
  3. Central venous blood
  4. Venous admixture
9.
Which cardiac reflex describes a rise in contractility in response to a raised heart rate?
  1. Anrep effect
  2. Bezold-Jarisch reflex
  3. Bainbridge reflex
  4. Treppe effect (did not mention Bowditch) – frequency dependent inotropy
10.
Omeprazole acts by
  1. Irreversibly binding H/Na/KATPase pump
  2. Reversibly binding H/Na/KATPase pump
  3. Irreversibly binding the H/K/ATPase pump
  4. Reversible binding of H/K/ATPase pump
11.
Which of the following neuromuscular junction blocking drugs can induce a Phase II block?
  1. Rocuronium
  2. Suxamethonium
  3. Vecuronium
  4. Pancuronium
12.
Which of the following factors INCREASE cerebral blood flow?
  1. Thiopentone
  2. Temperature <35deg
  3. PaCO2 <40mmHg
  4. PaO2 <40mmHg
13.
According to the Stewart Physiochemical approach to acid base which of the following is a dependable variable:
  1. HCO3
  2. pCO2
  3. Weak acid concentration
  4. Strong Ion Difference
14.
Which of the following stimulates bile secretion?
  1. Secretin
  2. Cholecystokinin
  3. Somatostatin
  4. Gastrin
15.
Mechanism of action of amphotericin
  1. Inhibition of cell wall synthesis
  2. Inhibition of DNA synthesis
  3. Formation of membrane pores (by binding to ergosterol)
  4. Inhibition of ergosterol synthesis
16.
The pH of saliva
  1. 6.8
  2. 5.6
  3. 1.5
  4. 8.5
The normal pH of saliva is 6.7 to 7.4
17.
The latent heat of vapourisation of water is:
  1. 2260 J/g
  2. 838 g/m3
  3. 213 J/g
  4. 44g/m3
For water at its normal boiling point of 100 ºC, the heat of vaporization is 2260 J g-1. This means that to convert 1 g of water at 100 ºC to 1 g of steam at 100 ºC, 2260 J of heat must be absorbed by the water.
18.
Which of the following most correctly describes the Bohr effect?
  1. A decrease in PaCO2 will decrease the affinity of oxygen for haemoglobin
  2. An increase in PaCO2 will promote oxygen offloading in the tissues
  3. A decrease in pH will decrease the affinity of oxygen for haemoglobin
  4. An increase in temperature will increase the affinity of oxygen for haemoglobin
19.
Which of these drugs has the SHORTEST context sensitive half time after a 12hr infusion?
  1. Midazolam
  2. Propofol
  3. Morphine
  4. Remifentanil
20.
What is the action of inhaled nitric oxide?
  1. Vasoconstriction with increased cGMP
  2. Vasoconstriction with decreased cGMP
  3. Vasodilation with increased cGMP
  4. Vasodilation with decreased cGMP