Q3ii: Outline the methods for assessing platelet function


Number / form

  • Platelet count → size + no.
  • Blood film → morphology


  • ACT, TEG/ROTEM, bleeding time


Light transmission platelet aggregation

  • Photo-optical measurement of light transmission ↑in relation to platelet aggregation
  • Screens for bleeding tendency, platelet defects & monitoring anti-platelet drugs

Shear stress

PFA – 100

  • Time evaluation of high shear whole blood flow blocked by platelet plug into a hole on activated surface
  • Assesses bleeding risk
  • Reveals vWD