R1v: Discuss temperature regulation specific to the neonate

Definition:

Neonate = birth to 28 days

Infant = 28 days to 1 year

Thermoregulation = the tight control of core body temperature despite fluctuating ambient temperatures

Mechanisms for Neonatal Temperature Regulation

In the TMZ body temperature is maintained by changing position and alterations in skin blood flow

Heat Balance in the Neonate – differs cf adults due to:

  • Heat Production
    • BMR twice that of adults
    • Therefore, must lose more heat to maintain body temp
  • Heat Loss
    • Smaller heat capacity → total mass of neonate is smaller, therefore total body heat energy is less.
    • Insulation minimal (thin subcut tissue)
    • Large SA:Vol → rapid heat loss, but also significant heat transfer to neonate in warming
    • Evaporation → high evaporative loses bc of increased skin perm
    • Insensible losses (especially with higher RR)
    • Limited ability to control personal environment

Cold Stress in Neonates:  Increased Symp NS stimulation = increase O2 & glucose consumption, Increased PVR, Increase R-to-L shunt, decreased peripheral perfusion & metabolic acidosis

Cold Responses

  • VC = limited
  • Shivering = not well developed
  • Behavioural = crying, change in position (much less effective cf adults)
  • Non Shivering Thermogenesis
    • Increased amount of brown fat (6% of total body wt of neonate)
    • Brown fat cells release Thermogenin
    • Uncouples oxidative phosphorelation = release of heat

Warm Responses

  • VD = limited
  • Sweating = limited capacity
  • Behaviour – crysing

Therefore, in a heat gaining environment, infants can only really dissipate heat via Insensible Losses → puts them at great risk of Hyperthermia