F11iii / 22A04: Describe the mechanisms of action and potential adverse effects of inhaled nitric oxide and prostacyclin
Eii / 22A02: Explain the mechanisms of transport of substances across cell membranes including appropriate examples (75% marks). Outline the structure and function of the Na+/K+-ATPase pump (25% marks)
L1iii / 22A12: Describe the process of excitation-contraction coupling and relaxation in smooth muscle
R1iv / 23B10 / 22A16: Outline the impact of sedative agents on thermoregulation (40%) and describe the physiological effects of a low body temperature (60%)
K4ii / 22A11: Outline the structure and function of the N-methyl-D-aspartate (NMDA) receptor (25% marks). Discuss the pharmacology of ketamine (75% marks).
K1i / 21B18: Outline the neural pathways for the pupillary light, corneal, oculomotor and gag reflexes. The anatomical course of nerves is NOT required
N2i / 21B07: Outline how the measurement of the following can be used in the assessment of liver function (25% marks of each) • Albumin • PT • Glucose • Ammonia
Q1iv / 21B19: Outline the process of fibrinolysis (40% marks). Write short notes on the indications, mechanism of action, pharmacokinetics and side effects of tranexamic acid (60% marks)
U1vi / 21B05: Write detailed notes on angiotensin, including its synthesis, role within the body and regulation
K2iv / 21B16: Classify the anti-psychotic drugs (25%). Outline the pharmacology of haloperidol (75% marks)
F6ii / 21B10: Describe the ventilation / perfusion (V/Q) relationships in the upright lung according to West’s zones (40%). Explain the physiological mechanisms responsible for these relationships (60%).
H2i / H3ii / 21B20: Describe the physical principles of haemodialysis and haemofiltration, including the factors affecting clearance (80% marks). Outline the key components of renal replacement fluids (20% marks).
Pvi / 21A04: Outline the dose (10% marks), composition (60% marks) and side effects (30% marks) of total parenteral nutrition (TPN)