Bii / 23A02: Describe the factors affecting drug absorption throughout the gastrointestinal tract

B SYL2017 / 22A01: Outline the effects of critical illness on drug pharmacokinetics, including examples

B SYL2017: Describe how pharmacokinetics are affected by ageing

Biv / 19B15: Define clearance and HER. Describe the role of the liver in drug clearance w examples

Biv / 16A08: Describe the characteristics of a drug that influence its excretion by the kidneys

Biv: Discuss the pharmacokinetic factors that affect drug half life

Bvi / 18A05: Compare and contrast the pharmacokinetic and pharmacodynamics of IV fentanyl and IV remifentanil (60 marks). Discuss the concept of context sensitive half-time using these drugs as examples (40 marks)

Bv: Zero & First Order Kinetics

Bvii: Explain clinical drug monitoring with regards to peak & trough concentrations, minimum therapeutic concentration & toxicity

Biv: Describe drug clearance, its determinants and how it is estimated

Biv / 16A20: Outline the role of the liver in drug pharmacokinetics

Biii / 18B07: Describe protein binding and its significance in pharmacology

Bii / 14A20: Describe the factors affecting drug absorption from the GI tract

Biii / 20A15 / 17B22: Define bioavailability (10 marks). Outline factors which affect it (90 marks)

Biii / 19A05 / 15B12: Volume of distribution

Bi: Explain the concept of pharmacokinetic modelling of single and multiple compartment models

B SYL2017: Neonate PK changes

Bviii: Describe the pharmacokinetics of drugs in epidural and subarachnoid space

B SYL2017: OBA with shock