Div: Loading dose, maintenance dose & critically ill

Diii: Outline the pharmacokinetic consequences of old age with examples

Diii: Describe the effects of obesity on drug pharmacology and give examples of drugs to illustrate

Dii / 21B15 / 17A03 / 15A09: Classify and describe mechanisms of drug interactions with examples

Dvii: Explain the mechanisms and significance of pharmacogenetic disorders

Di / 17B16: Classify and describe adverse drug reactions with examples of each

Dvii: Outline genetic variability

Dviii: Describe & give examples of the clinical importance of isomerism

Dvii: Discuss factors contributing to the inter-individual variability in response to opioid analgesics

Dvi / 14B15: Define the terms tolerance and tachyphylaxis (20 marks). Describe the different mechanisms by which tolerance can develop and give examples of each (80 marks)

Dv: Define Tachyphylaxis, Tolerance, Addiction, Dependence & Idiosyncrasy

Div: How does liver failure affect pharmacology of drugs

Div: Outline alterations to drug response due to critical illness