Syllabus
G: Cardiovascular System
- G3iii / 14B19: Describe the factors that determine RV & LV afterload
- G3iii / 15B15: Define cardiac preload and describe its determinants
- G3iii / 16A13: Describe the cardiovascular effects of a sudden increase in afterload
- G3iii / 18B18: Describe the factors affecting LV function
- G3iii / 20B18: Define afterload & describe the physiological factors that may affect afterload
- G3iii / 23B17: Describe the consequences for the left ventricle of a sudden and sustained increase in afterload
- G3iii / 24AQ3: The systemic vascular resistance is suddenly increased, describe the consequences for the otherwise healthy left ventricle
- G3iii: LA pressure curve
- G3iii: Regulation of the heart
- G3iii: Define myocardial contractility & describe dPdT, ESPVR, Ejection Fraction
- G3iii: Describe the factors that affect output of the RV
- G4iii / 15B03: Compare and contrast renal and hepatic blood flow, and their regulation
- G4iii / 18A07: Splanchnic Blood Flow
- G4iii / G1ii / 18A11 / 14B10: Describe the adult coronary circulation and its regulation
- G4iii / K1iii / 24A14 / 23B14 / 21A20 / 14A14: Cerebral Blood Flow
- G4iii / O1iv / 18A07: Outline the blood supply to the gastrointestinal system
- G4iii: Define a portal system. Describe the anatomy & function of three portal systems in the body
- G4iii: Spinal cord blood flow
- G4iii: Table of Regional Blood Flows
- G4iii: Uteroplacental Blood Flow
- G5i / 15A19: Describe the effects of ageing on the cardiovascular system
- G5i / 20B11: Describe the changes in the circulatory system that occur during exercise.
- G5i / 22B12: Describe the effects of ageing on the cardiovascular system
- G5i: Cardiovascular response to haemorrhage
- G5i: Cardiovascular responses to anaemia
- G5i: The cardiovascular response to central neural blockade
- G5i: The systemic cardiovascular response to exercise
- G5i: Describe the compensatory mechanisms in a fit person moving from supine to standing position
- G6ii / 18A18: Compare & contrast non-invasive oscillometric and invasive arterial blood pressure monitoring
- G6ii / 19A02: Components required to measure blood pressure from an intra-arterial catheter
- G6ii / 20A12 / 17B17 / 15A12: Effects of resonance damping on invasive IABP tracing
- G6ii / 22B10 / 16B17: Aortic vs Radial waveform
- G6ii: NIBP Monitoring – Auscultation with Sphygmomanometer
- G6iii / 17B10: Compare and contrast two methods of measuring cardiac output
- G6iii / 19A08: Compare and contrast the measurement (40% of marks) and interpretation (60% of marks) of both central venous and mixed venous oxygen saturations
- G6iii / 21B03 / 14A19: CO Thermodilution
- G6iii: Describe the principles & limitations of the measurement of cardiac output using PICCO
- G6iii: Techniques/measurements that are available to assess the circulation of a patient in ICU
- G6iii: Waveforms & pressures seen in each anatomical location during insertion of a PAC
- G7i / 14B01: Classify commonly used inotropic agents & describe their mechanism of action
- G7i / 16B15: Compare and contrast the pharmacology of noradrenaline and dobutamine
- G7i / 17B15: List the properties of an ideal inotope. How does adrenaline compare to these ideal properties
- G7i / 18A02: Compare and contrast the pharmacology of adrenaline and milrinone
- G7i / 19B18: Compare and contrast the pharmacology of metaraminol and noradrenaline
- G7i / 20A10: Compare and contrast the pharmacology of noradrenaline and vasopressin
- G7i / 20B15: Compare and contrast the pharmacology of dobutamine and levosimendan
- G7i / 21A01: Describe the pharmacology of adrenaline
- G7i / 22B13: Compare and contrast the pharmacology of EPHEDRINE and METARAMINOL
- G7i / 23A20: Compare and contrast the relevant pharmacology of intravenous adrenaline andvasopressin
- G7ii / 16B02: Compare and contrast the mechanisms of action and toxicity of sodium nitroprusside and glyceryl trinitrate (GTN)
- G7ii / 17B08: Classify calcium channel antagonists and give one example of each class
- G7ii / 20A02: Describe the pharmacology of glyceryl trinitrate
- G7ii / 20B20 / 15A11: Outline the pharmacology of sodium nitroprusside Discuss the mechanisms of toxicity and their management
- G7ii: Pathophysiological basis for using ACEi + ARB in HF
- G7ii: Classify antihypertensive agents by their MoA + Outline each mechanism briefly + Give an example of a drug from each class
- G7iii / 16B21: Classify anti-arrythmic drugs by mechanism of action, giving examples of each (75 marks). Describe the electrophysiological and ECG effects of sotalol (25 marks)
- G7iii / 18B02: Compare and contrast amiodarone and digoxin
- G7iii / 19A14: Compare and contrast the MoA, PK and AE of digoxin and sotalol
- G7iii / 21B09 / 19B14: Outline the classification and effects of beta-blocking drugs with examples (50% marks). Compare and contrast the pharmacokinetics of metoprolol with esmolol (50% marks)
- G7iii / 21B11 / 16A11: Provide a detailed account of the side effects of Amiodarone
- G7iii / 22A05: Write short notes on the pharmacology of labetalol and esmolol, highlighting their differences
- G7iii / 22B08 / 14A02: Classify CCB. Pharmacolgy of Verapamil
- G7iii / 23A11: Outline the Vaughan Williams classification of anti-arhythmic drugs with examples (30% of Marks). Describe the relevant pharmacology of adenosine (70% of Marks)
- G7iii / 24A19 / 14B13: Outline the pharmacology of Amiodarone
- G7iii: β-Adrenoreceptor Antagonists